Medication skin reactions can arise due to various causes and present in different types. Allergic reactions are common, where the immune system perceives the drug as harmful, leading to rashes, hives, or itching. Non-allergic reactions can result from direct skin irritation by certain medications. Photosensitivity reactions are triggered by sunlight exposure after taking photosensitizing drugs. Severe forms include Stevens-Johnson syndrome and toxic epidermal necrolysis, often triggered by certain antibiotics or antiepileptic medications. Drug-induced hypersensitivity reactions affect multiple organs and may be life-threatening. Additionally, interactions with other medications or individual factors like genetics can also contribute to these skin reactions. Careful monitoring and prompt medical attention are vital for managing such conditions.